NCCR-Synapsy

The Synaptic Bases of Mental Diseases

Neural signature of trait anxiety

The neurological basis of trait anxiety, a risk factor for the development of neuropsychiatric diseases, revealed by Synapsy researchers. Trait anxiety is a personality dimension related to the extent to which events are perceived as potentially threatening. The identification of Read more…


Maternal exposure to violence and child psychopathology

Synapsy has been following the children of mothers suffering from post-traumatic stress disorder due to interpersonal violence since they were 12 months of age. They are now reaching maturity, just like research projects designed to understand and treat stress-related disorders. Read more…


Phase-3 : Synapsy ranked at the top by the SNSF

networking

Entering Phase-3 has been achieved following a long preparatory and competitive process involving coordinated work from NCCR members at all levels. At the end of January 2019, the Synapsy management team received from the Swiss National Science Foundation (SNSF) the Read more…


ASD : Protein synthesis as a possible biomarker

Eleonora Rosina

Eleonora Rosina   Highlight from the Bagni’s Lab Genes encoding for proteins involved in synaptic protein synthesis seem to contribute to the development of Autism Spectrum Disorders. They are now suspected as early biomarkers. Eleonora Rosina, a PhD student in Read more…


Social dopamine

Dopaminergic

Dopaminergic neurons of the VTA (green). Virus-infected neurons that can be inhibited to assess their effects on social behavior through chemogenetic approaches are in red. The level of infected dopamine neuron is about 50% (yellow).   Highlight from the Bellone’s Read more…


Synapsy enters Phase-3 with new challenges

ANNUAL MEETINGS 3

The Synapsy Group – Villars 2018 Following a successful Site-Visit, Synapsy has officially entered Phase-3 in October 2018. A final decision regarding the overall funding for Synapsy’s third phase is expected from the Swiss National Science Foundation (SNSF) in January Read more…


The brain is fighting against autism

eye-tracking

Eye-tracking experience Each dot indicates the position of the gaze while viewing a video showing a child playing. Left : the blue dots are the areas targeted by a child with typical cerebral development. Right : the red dots are targeted by Read more…


Early psychoses

Coronal, sagittal and axial views

NAC improves fornix integrity in parallel to the increase of brain glutathione and cognition improvement. 6-month longitudinal gFA changes : NAC vs Placebo. Coronal, sagittal and axial views show voxel-wise analysis results indicating location (body of the fornix) of time Read more…


Synapsy sets it course for 2022, borne along by rising synergies

WP2 team

Do/Conus Team Members. From left to right, front : Sara Camporesi, Gloria Reuteler, Ines Khadimallah, Adeline Cottier, Kim Do Cuénod, Martine Cleusix, Margot Fournier, Lijing Xin; behind : Clémentine Vincent, Raoul Jenni, Guillaume Marillier, Pascal Steullet, Paul Klauser, Philipp Baumann, Gilles Allenbach, Read more…