NCCR-Synapsy

The Synaptic Bases of Mental Diseases

The synaptic interactions driving the neural circuit computations underlying any goal-directed sensorimotor transformation

sensory-process in mouse

The research undertaken by Prof. Carl Petersen and his group about the causal description of the synaptic interactions driving the neural circuit computations underlying any learned, goal-directed sensorimotor transformation is published in Nature Neuroscience. Sensory perceptions are thought to be Read more…


Nobel Prize 2013 : Thomas Südhof, a pioneer of synaptic mechanisms

thomas sudhof portrait

Thomas Südhof Ralf Schneggenburger shares his views on the 2013 Nobel Prize in Physiology or Medicine laureate. The 2013 Nobel Prize honours three scientists who have solved the mystery of how the cell organizes its transport system, and how vesicles Read more…


Cocaine tampers with the brain’s brakes

cocaine leaves

New results from Christian Lüscher and his group show that cocaine not only acts on excitatory transmission but also affects inhibitory transmission provoking loss of an intrinsic brake in the brain. Cocaine-evoked synaptic plasticity in the nucleus accumbens and the Read more…