Dr. Guillaume Marillier will work in the conus/do-lab in WP#2. His project will aim to investigate the role of redox dysregulation in auditory sensory deficits experienced by early psychosis patients.
Although low-level auditory sensory processing deficit has been proposed as a potential key pathophysiological mechanism of early psychosis, the underlying mechanism of its deficit is still unclear. Based on the TIPP cohort of early psychosis patients, which have been fully phenotyped at the levels of structural, functional and neurochemical imaging as well as of peripheral redox/inflammatory markers, Dr. Marillier will explore the critical role of redox dysregulation/neuroinflammation in these sensory gating impairments.