NCCR-Synapsy

The Synaptic Bases of Mental Diseases

Editorial – Synapsy and Genetics: an Adventure Ahead

by Alexandre Dayer   From a historical perspective, early hypotheses about risk genes in psychiatry were based on candidate gene approaches and were largely incorrect. These studies were performed in small-sized cohorts and led to a replication crisis. However, in Read more…


Genetics and psychiatry: Using Genetic Variants to Stratify the Enormous Heterogeneity of Patients

Genetic variants have an effect on our appearance, functioning and health. Synapsy is taking a detailed look at their association with psychiatric illness phenotypes. Following the success of the first two Synapsy phases, the time has come to begin to Read more…


Kerstin Von Plessen – Treatments Based on Self-Regulation

Kerstin von Plessen studies early biomarkers and potential resilience pathways for treating neurodevelopmental illnesses – areas that require a translational approach. As well as being a full professor in the Faculty of Biology and Medicine at the University of Lausanne Read more…


Empowerment: Three Questions for Bita Moghaddam

Bita Moghaddam is a full professor at Oregon Health and Science University where she holds the Chair of the Department of Behavioral Neuroscience. In the past 26 years, she focused her research on the modeling aspects of psychiatric disorders. Last Read more…


Nathalie Ginovart – Translational Research Using Neuroimaging

Nathalie Ginovart uses neuroimaging as a research tool to investigate mental disorders and as a way of bringing the clinical and fundamental worlds closer together. Nathalie Ginovart started by studying biology before continuing with a master’s in pharmacology followed by Read more…


Denis Jabaudon – Synapsy is Developing a Common Culture

Denis Jabaudon is a professor of neuroscience and current director of the Department of Basic Neuroscience at the University of Geneva. He is also an attending physician in the Department of Neurology at the University Hospital of Geneva (HUG). Professor Read more…


Antje Horsch – Deciphering the Inter-Generational Transmission of Stress and Trauma

Antje Horsch holds the position of assistant professor at the Institute of Higher Education and Research in Health Care at the University of Lausanne (UNIL) and in the Women and Children’s Department at Lausanne University Hospital (CHUV). Professor Horsch, who Read more…


Alexandre Reymond – Puzzled About the Way Nature Works

Alexandre Reymond has a dual biochemical and biological background with undergraduate studies at the University of Lausanne (UNIL). Alexandre entered research via a PhD at the Swiss Institute of Experts on Cancer Research (ISREC) before continuing with a post-doctoral fellowship Read more…


Emmanouil Dermitzakis – “Producing Something Together is so Rewarding!”

Emmanouil Dermitzakis is from Heraklion in Greece. After studying biology at the University of Crete, Emmanouil completed a PhD in genetics at Penn State University. He then joined the University of Geneva as a post-doctoral fellow in the laboratory led Read more…