NCCR-Synapsy

The Synaptic Bases of Mental Diseases

Interneuron plasticity initiates the rewiring of the auditory cortex

interneurons plasticity

 EPFL neuroscientists have found that the output synapses of certain interneurons in the cortex show long-term plasticity. This plasticity occurs during a critical period of brain development and might contribute to the experience-dependent rewiring of brain circuits. Interneurons inhibit the Read more…


Astrocytes are involved in personality disorders

A new Study conducted by the Synapsy researcher Paola Bezzi and published in the Journal of Molecular Psychiatry shows that neuronal development in the prefrontal cortex and associated cognitive processes, depend on the proper functioning astrocytes. Paola Bezzi and her Read more…


MD-PhD fellowship awarded to Aurélie Bochet

aurelie bochet

The SNSF, the SAMS and the Swiss cancer research foundation will support ten young medical researchers in doing their MD-PhDs. The national MD-PhD commission has awarded fellowships to 10 of the 23 medical researchers proposed by the local MD-PhD commissions. Read more…


Philippe Conus elected Vice President of IEPA

Philippe Conus IEPA

Philippe Conus, ordinary professor at the FBM-UNIL and head of the General Psychiatry Department of the CHUV, has been elected vice-president for Europe of the IEPA-Early Intervention in Mental Health, an international scientific society that aims to promote early intervention Read more…


Amputees consider their prosthetic limb is an extension of their own body

prosthetic arm

Merely having the prosthetic limb is not enough to assist the amputees with their activities. Many amputees skip the extended use of their prosthetic limb as their misplaced limb does not meet the criteria of their prosthesis. This actually means that Read more…


Researchers find dominant men can make decisions faster

boss shouting

Men who exhibit high social dominance make faster decisions than low-dominance men even outside a social context, finds a large behavioral study from EPFL. Hierarchies exist across all human and animal societies, organized by what behavioral scientists refer to as Read more…


Autism social interaction difficulties caused by poor synapse maturation

Dopamine

A significant debilitating factor for those afflicted with autism spectral disorders (ASD) is impairment of social communication. Now, a team of investigators from the Universities of Geneva (UNIGE) and Basel (UNIBAS), in Switzerland believe they have uncovered what happens in Read more…


Targeting a brain mechanism could treat aggression and violent behavior

brain targetting

EPFL neuroscientists have identified a brain mechanism that is linked to aggression and violent behavior, potentially forming the basis for treating aggression in several psychiatric disorders. Violence, which, needless to say, are destructive to both individuals and societies worldwide: death, Read more…


Budding Clinical-Scientists

Budding clinician scientists-web

Vincienne Naef, Grace Kurian and Marc-Aurèle Adler Vincienne Naef, Grace Kurian and Marc-Aurèle Adler are third and fourth year medical students at the University of Geneva. All three attended the Neurobiology of Mental Health conference, an ideal opportunity for Synapsy Read more…