NCCR-Synapsy

The Synaptic Bases of Mental Diseases

Obsessive Compulsive Disorders: How to treat OCD?

The fourth most common psychiatric illness, OCD affects between 2 and 3% of the population. Obsessive compulsive disorder, called OCD, is a psychological disorder. It is characterized by distressing obsessions that occur as recurring mental thoughts or images. These lead Read more…


Optimus Agora Prize for Carmen Sandi and Dominique de Quervain

Dominique de Quervain and Carmen Sandi are being awarded Optimus Agora Prize. Their project “Stress” encourages interaction with the public. Stress is part of everyday life. Better understanding it, and knowing how to prevent situations that cause it, improves our Read more…


covidout.ch: maintaining mental health and developing coping skills

The objective of this new web app, designed by caregivers and researchers, is to help people with temporary/reactional or chronic psychological suffering to find coping strategies to better cope with the crisis in the broadest sense: health, containment, de-confinement, post-confinement, Read more…


New EEG Study on Euthymic Bipolar Disorder Patients

Bipolar disorder (BD) is a common and severe psychiatric disorder. A better understanding of the underlying pathophysiology is needed to identify objective biomarkers of BD that would improve diagnostic and treatment. Evidence from brain imaging studies consistently points to abnormalities Read more…


World Congress of Biological Psychiatry 2019

Synapsy was present at the 14th World Congress of Biological Psychiatry 2019 in Vancouver with its two members, Camille Piguet (UNIGE) and Jean-Michel Aubry (HUG). The latter was the chair of the seminar entitled “Relevant neuroimaging biomarkers in offspring of Read more…


Impulsivity increases with severity of childhood trauma in bipolar disorder

impulsivity

In the context of the WP#5, the clinical dimension of impulsivity was studied in people with attention deficit disorder either with or without hyperactivity (ADHD), borderline personality disorder (BPD) or bipolar disorder (BD). This study showed a high level of Read more…


Two EPFL spin-offs reach the finals of an international competition

hello tomorrow

EPFL spinoffs Lumendo and GliaPharm are among 80 deep-tech startups from around the world that have qualified for the finals of the Hello Tomorrow Challenge in Paris tomorrow. The finalists will pitch their company to a jury of technology specialists Read more…


Lactate triggers genes that modify brain activity

Fluorescent neurons

Fluorescently labeled neuronal dendritric ramifications. © KAUST   A genome-wide study led by Pierre Magistretti has shed light on the mechanisms through which lactate, a product of aerobic glycolysis in astrocytes, regulates long-term memory formation and neuroprotection. Specifically, the team found Read more…


L-Lactate: from neural network potentiation to neuroprotection

magistretti publication

NMDA receptors are involved in several aspects of fundamental brain functions, as well as in a variety of neurological disorders. In its last study published in the Nature series “Scientific Report”, the laboratory of Pierre Magistretti reveals that L-Lactate is a Read more…