NCCR-Synapsy

The Synaptic Bases of Mental Diseases

Impulsivity increases with severity of childhood trauma in bipolar disorder

impulsivity

In the context of the WP#5, the clinical dimension of impulsivity was studied in people with attention deficit disorder either with or without hyperactivity (ADHD), borderline personality disorder (BPD) or bipolar disorder (BD). This study showed a high level of Read more…


Two EPFL spin-offs reach the finals of an international competition

hello tomorrow

EPFL spinoffs Lumendo and GliaPharm are among 80 deep-tech startups from around the world that have qualified for the finals of the Hello Tomorrow Challenge in Paris tomorrow. The finalists will pitch their company to a jury of technology specialists Read more…


Lactate triggers genes that modify brain activity

Fluorescent neurons

Fluorescently labeled neuronal dendritric ramifications. © KAUST   A genome-wide study led by Pierre Magistretti has shed light on the mechanisms through which lactate, a product of aerobic glycolysis in astrocytes, regulates long-term memory formation and neuroprotection. Specifically, the team found Read more…


L-Lactate: from neural network potentiation to neuroprotection

magistretti publication

NMDA receptors are involved in several aspects of fundamental brain functions, as well as in a variety of neurological disorders. In its last study published in the Nature series “Scientific Report”, the laboratory of Pierre Magistretti reveals that L-Lactate is a Read more…


Roland Hasler at the International ADHD Congress in Tel Aviv

Roland Hasler giving a conference

Roland Hasler presenting –  March 2018 Dr Roland Hasler presented Synapsy’s research on electroencephalogram (EEG) Neurofeedback on adult patients with Attention Deficit Hyperactivity Disorder (ADHD). Neurofeedback (NF) uses EEG brain-computer interface to give participants a real-time feedback about their brain Read more…


Survey: Switzerland has a mental health Röstigraben

man struggling

People in French and Italian-speaking parts of Switzerland are nearly twice as likely to feel depressed as those in German regions, according to a report. Residents of the cantons of Vaud and Ticino are most likely to suffer from feelings Read more…


Change the way you see your life ! (SNSF Image Competition)

Image competition

A patient with severe attention deficit is playing a video game. The goal is to pilot a space shuttle with the brain by means of an electrode placed in the parietal region. As the game progresses, the patient player is Read more…


3D Imaging removes secrets of communication between brain cells

3D-Imaging

Prof. Andrea Volterra and his team from the Department of Fundamental Neuroscience (UNIL) have pioneered a new approach allowing correct study of astrocyte-synapse-blood vessel interactions: 3D volumetric two-photon imaging. This method enables an unprecedented, comprehensive view of the multiform astrocyte Read more…


Could “forgetting” be the cure to addictions

Erasing addictions

The research groups of Dr Benjamin Boutrel, PD, MER1 from the Psychiatry Department, Faculty of Biology and Medicine, CHUV and Prof. Pierre Magistretti from the University of Lausanne and the EPFL published an article in the prestigious journal Molecular Psychiatry Read more…