The Synaptic Bases of Mental Diseases

Anxiety: Brain Mitochondria as a Treatment Target

Carmen Sandi, professor at EPFL’s Brain Mind Institute and co-director of the NCCR-Synapsy, published a review on the connection between anxiety and brain mitochondriain the Journal Trends in Neurosciences with her colleague Michaela Filiou from the Max Planck Institute.They highlight scientific data linking mitochondrial dysfunction to various psychiatric disorders and point out experimental evidence suggesting the involvement of specific mitochondrial and metabolic factors in anxiety. The two researchers are calling for pharmacological manipulation of brain mitochondria to treat anxiety symptoms.

Original publication :

Legend : Electromicrography showing neuron mitochondria (dashed white line) ©Carmen Sandi

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