NCCR-Synapsy

The Synaptic Bases of Mental Diseases

Identification of a behavioral and neural signature of trait anxiety related to differences in effortful motivated behavior

The combined expertise of Carmen Sandi and Christoph Michel’s labs allowed to better understand the neurological basis of trait anxiety, a risk factor for the development of neuropsychiatric diseases. Trait anxiety is a personality dimension related to the extent to Read more…


Making mental health a global priority

Who hasn’t felt a sense of loss or detachment from our families, friends, and regular routines, or experienced nervousness and anxiety about changes in our personal and professional lives? For some, fear and worry constantly distract, confuse, and agitate. For Read more…


Hierarchy in animals: Anxiety can kill your social status

Anxiety cells

Mitochondria in the neurons of the nucleus accumbens. Neuroscientists at EPFL identify a brain region that links anxious temperament to low social status. The researchers were able to tweak social hierarchy in animals by using vitamin B3. There are important Read more…