NCCR-Synapsy

The Synaptic Bases of Mental Diseases

Post-traumatic pain expressed physically from generation to generation

A Synapsy article has demonstrated that mothers suffering from post-traumatic stress disorders resulting from domestic violence often convert their mental suffering into physical pain and pass on this somatisation to their children. Adults who have suffered childhood trauma exhibit a Read more…


Get More or Give Up, a Question of Anxiety

Individuals can respond to stress in diametrically opposed ways. A NCCR-Synapsy study shows that the behavioral response depends on the level of anxiety and identifies the cerebral mechanisms involved. People often have different responses to stress. These distinct behavioral reactions Read more…


Connecting stress, weight, and social anxiety in early adolescence

Scientists at EPFL have found a biological connection explaining why there is an increased predisposition to develop obesity and being less sociable in individuals that have experienced stress during early puberty.   Between the end of childhood and the beginning Read more…


A mother’s lack of empathy impacts her child’s mental health

A Synapsy study shows that mothers with post-traumatic stress disorder due to interpersonal violence misread their children’s emotions due to a lack of emotional comprehension, a difficulty that, in turn, has been associated with their children’s level of aggressive behavior Read more…


Overcoming long-term trauma can be facilitated

Older traumatic experiences are harder to get over compared to recent ones, and Synapsy scientists based at EPFL have started to understand why – at the level of brain circuits in mice. The results point the way for treating long-term Read more…


Virginie Perizzolo’s work awarded prize

The 11th French Congress of Psychiatry (CFP) awarded Best Scientific Publications of 2019 by Young Researchers Prize, 3rd Place to Virginie Perizzolo (née Pointet) of the University of Geneva, for her paper with Synapsy member Daniel Schechter: “EEG recording during Read more…


New EEG Study on Euthymic Bipolar Disorder Patients

Bipolar disorder (BD) is a common and severe psychiatric disorder. A better understanding of the underlying pathophysiology is needed to identify objective biomarkers of BD that would improve diagnostic and treatment. Evidence from brain imaging studies consistently points to abnormalities Read more…


Johannes Gräff appointed Vallee Scholar

The Valle Foundation has chosen EPFL Professor and Synapsy member Johannes Gräff among the winners of its scholarships. The Vallee Foundation was founded in 1996 by Bert and Kuggie Vallee “to foster originality, creativity, and leadership within biomedical scientific research and medical Read more…


Anxiety: Brain Mitochondria as a Treatment Target

Carmen Sandi, professor at EPFL’s Brain Mind Institute and co-director of the NCCR-Synapsy, published a review on the connection between anxiety and brain mitochondriain the Journal Trends in Neurosciences with her colleague Michaela Filiou from the Max Planck Institute.They highlight Read more…