The Synaptic Bases of Mental Diseases

Deciphering the emergence of neuronal diversity

Inhibitory interneurons labelled with a fluorescent molecule (in green) are distributed in the cerebral cortex. These cells were individually isolated and single cell transcriptomics revealed markers (in white) specifically expressed in distinct sub-groups of interneurons. The development of cerebral cortex Read more…

Impaired regulation of serotonin affects positioning of brain cells

Serotonin cells

In a study of infant mice, researchers have found that the positioning of brain cells is affected by early-life impairment of the system that regulates serotonin — a key brain chemical targeted by antidepressants and known to regulate mood. Like Read more…

A new role for serotonin in psychiatric vulnerability


Prof Dayer’s team has unveiled the crucial role of a serotonin receptor in the assembly of brain circuits. Serotonin, a neurotransmitter in our brain, is at the root of our moods. Research has shown that poor regulation of the serotonin Read more…