NCCR-Synapsy

The Synaptic Bases of Mental Diseases

SHANK3 controls maturation of social reward circuits in the VTA

shShank3 Imagery

The autism spectrum disorders are a heterogeneous group of neurodevelopmental disorders whose main characteristic alterations in social communication, restricted interests and repetitive behaviors. If the assumptions to identify alterations in brain circuits that could be responsible for autism disorders are Read more…


How chronic stress tears us apart

stress-apart

Chronic stress can lead to behavioral problems. Prof Carmen Sandi’s team has discovered an important synaptic mechanism: the activation of a cleaving enzyme, leading to these problems. Why is it that when people are too stressed they are often grouchy, Read more…