The Synaptic Bases of Mental Diseases

Lactate triggers genes that modify brain activity

Fluorescent neurons

Fluorescently labeled neuronal dendritric ramifications. © KAUST   A genome-wide study led by Pierre Magistretti has shed light on the mechanisms through which lactate, a product of aerobic glycolysis in astrocytes, regulates long-term memory formation and neuroprotection. Specifically, the team found Read more…

L-Lactate: from neural network potentiation to neuroprotection

magistretti publication

NMDA receptors are involved in several aspects of fundamental brain functions, as well as in a variety of neurological disorders. In its last study published in the Nature series “Scientific Report”, the laboratory of Pierre Magistretti reveals that L-Lactate is a Read more…