NCCR-Synapsy

The Synaptic Bases of Mental Diseases

Low-dose diazepam can increase social competitiveness

Anxiety

EPFL scientists have discovered how low-dose anxiolytics increase the social competitiveness of high-anxious individuals by boosting the energy output of mitochondria in an area of the mammalian brain that controls motivation and reward. Psychologists speak of anxiety in two forms: Read more…


How social rank can trigger vulnerability to stress

mice in nest

EPFL scientists have identified rank in social hierarchies as a major determining factor for vulnerability to chronic stress. They also show that energy metabolism in the brain is a predictive biomarker for social status as well as stress vulnerability and Read more…


Prof. Carmen Sandi nominated President-elect of the FENS

Carmen Sandi FENS nomination

  On July 2, 2016, Prof. Carmen Sandi, Director of the Brain Mind Institute at the School of Life Sciences, EPFL, was elected President-elect (term as President starting in 2018) of the Federation of European Neuroscience Societies (FENS) in the Read more…


Hierarchy in animals: Anxiety can kill your social status

Anxiety cells

Mitochondria in the neurons of the nucleus accumbens. Neuroscientists at EPFL identify a brain region that links anxious temperament to low social status. The researchers were able to tweak social hierarchy in animals by using vitamin B3. There are important Read more…


Professor Carmen Sandi has been awarded the Valkhof Chair 2015

Carmen Sandi

Prof. Carmen Sandi has been awarded the Valkhof Chair 2015. On June 22nd, she had the opportunity to give this year’s Valkhof Lecture, entitled: “The stressed social brain: from rodents to humans”. The Executive Board of Radboud university medical center Read more…


Two young researchers awarded at the 2nd DNF Symposium

Best poster reward

P. Bezzi, C. Bellone, F. Petrelli, S. Habbas During the 2nd DNF Symposium held at the DNF/CHUV, two young scientists working within the NCCR Synapsy received the 1st and 2nd poster prizes : Samia Habbas (Prof. Volterra lab) and Francesco Read more…


Stress and the social brain : effects and mechanisms

2 social brains

Prof. Carmen Sandi has published a review article in Nature Reviews Neuroscience on stress and the social brain. As noted in a review article by Carmen Sandi (> LGC lab), from the Brain Mind Institute at EPFL and József Haller, Read more…


How stress affect self-confidence during competition time

man stressing

How does stress affect our self-confidence when we compete? An EPFL study shows how stress could actually be both a consequence and a cause of social and economic inequality, affecting our ability to compete and make financial decisions. Stress is Read more…


How chronic stress tears us apart

stress-apart

Chronic stress can lead to behavioral problems. Prof Carmen Sandi’s team has discovered an important synaptic mechanism: the activation of a cleaving enzyme, leading to these problems. Why is it that when people are too stressed they are often grouchy, Read more…