The Synaptic Bases of Mental Diseases

The rewarding work of translational projects

Team CB-MS

Camilla Bellone and Marie Schaer work in collaboration under the NCCR-Synapsy project.

Camilla Bellone explores the use of animal models in social paradigms, to look at the causality between circuitry and mechanism and behaviour. Her recent work looks at dopaminergic neurons and the dysfunction in the reward system that shows social impairments in mice. Indeed, these impairments can be detected as structural changes in the reward system in human pre-schoolers.

Using a range of techniques, from MRI and EEG, and eye-tracking Marie Schaer has been able to explore the neural networks involved in social interaction and stimuli. The reciprocal relationship between Camilla’s and Marie’s research projects have been focused on the social motivation hypothesis, but not everything is social in ASD.

In this video-interview (8’35”), they explain a little of their findings and how they work in this NCCR-Synapsy translation project.

They will present in further detail as state of the art speakers in Vienna >.

Author : ESCAP >

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